HUMAN THERMAL COMFORT AND HEAT STRESS IN AN OUTDOOR URBAN ARID ENVIRONMENT: A CASE STUDY


Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol

Cells employ regulated transport mechanisms to ensure that their plasma membranes (PMs) are optimally supplied with cholesterol derived from uptake of low-density lipoproteins (LDL) and synthesis.To date, all inhibitors of cholesterol transport block steps in lysosomes, limiting our understanding of post-lysosomal transport steps.Here, we establish

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Development of an exercise intervention for the prevention of musculoskeletal shoulder problems after breast cancer treatment: the prevention of shoulder problems trial (UK PROSPER)

Abstract Background Musculoskeletal shoulder problems are common after breast cancer treatment.There is some evidence to suggest that early postoperative exercise is safe and may improve shoulder function.We describe the development and delivery of a complex intervention for evaluation within a randomised controlled trial (RCT), designed to target

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